Guillaume Girier | Postdoc Researcher

“With four parameters I can fit an elephant, and with five I can make him wiggle his trunk.”

- John von Neumann

Photo of Guillaume Girier


HELLO WORLD!



Guillaume Girier holds a PhD in Computational Neuroscience, awarded cum laude in 2024, with a focus on investigating the excitatory thresholds of single-neuron models through an integrative approach combining computational modeling, simulations, and experimental validation.

He is currently a postdoctoral researcher in the Complex networks and brain dynamics group (COBRA) in Prague, where his primary focus lies in modeling epilepsy using neural mass models and detailed neuronal microcircuits. His research aims to uncover the mechanistic underpinnings of epileptogenesis and seizure dynamics by bridging theoretical frameworks with experimental data.

His overarching objective is to bridge computational modeling and experimental neuroscience to create a bidirectional framework where models inform experiments, and experimental findings refine the models. By establishing this iterative feedback loop, his work seeks to consolidate knowledge between theoretical and experimental approaches, enabling a deeper understanding of neural excitability and seizure dynamics.

Last update: 12/03/2025

News



Date Event Links
July 5-9, 2025
Incoming
"Computational strategies in epilepsy modelling and seizure control" Workshop at the 34th Annual Computational Neuroscience Meeting.
CNS*2025, Florence, Italy.
More information: Link
BRADY Webpage: Link
June 17-20, 2025
Incoming
"Ion Dynamics Underlying the Seizure Delay Effect of Low-Frequency Electrical Stimulation" poster presentation.
International Conference on Mathematical Neuroscience, Barcelona, Spain.
More information: TBA
ICMNS webpage: Link
June 2-6, 2025
Incoming
"Ion Dynamics Underlying the Seizure Delay Effect of Low-Frequency Electrical Stimulation" poster presentation.
International Conference for Technology and Analysis of Seizures, Montréal, Canada.
Assigned Poster Session Date: June 4, 2025, 1:00 PM - 2:00 PM
Room: A.01.9209 (Ground floor)
Space Number: 122
More information: TBA
ICTALS webpage: Link
April 4, 2025 "Ion Dynamics Underlying the Seizure Delay Effect of Low-Frequency Electrical Stimulation" preprint.
DOI : Link
September 01, 2024 New Postdoc position in the Complex Networks and Brain Dynamics (COBRA) group.


Github Repositories



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Coming soon

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Image 1

Ion Dynamics Underlying the Seizure Delay Effect of Low-Frequency Electrical Stimulation

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Image 2

PhD thesis

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Image 3

High-Order-Interactions-Python

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Image 4

Emergence of High Order Functional Hubs in the Human Brain

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SKILLS



Modelling Data Analysis Programming Laboratory
Point, population, microcircuit neuron models Big Data Analysis Python / Cython / Jupyter Notebook Immunostaining
Linear algebra, calculous Time Series Analysis Matlab Western blot
Bifurcation Analysis & Numerical Continuation Statistical Analysis C Fluorescence Microscopy
Slow-Fast decomposition Classification & Machine Learning Bash Electrical Circuit
Model fitting based on data Dynamic Alignments R ELISA assay
Neural Networks and Machine learning Reccurence Structure Analysis Mathematica Patch-Clamp